Fig. 7
Enrichment analysis of functional pathways of differentially expressed genes related to TME stromal and immune scores in Caucasian and Asian LUAD patients. A–D GO barplots (left) and bubble plots (right) of functional pathways enrichment analysis of TME stromal and immune scores-related differentially expressed genes in Caucasian (up) and Asian (down) LUAD patients. Left: GO barplots for GO functional pathway enrichment analysis of differentially expressed genes related to TME scores. The abscissa represents gene count enriched in this pathway, and the ordinate represents the names of various pathways. The red represents a high degree of enrichment, and the blue represents a low degree of enrichment. Right: GO bubble plots for GO functional pathway enrichment analysis of differentially expressed genes related to TME scores. The abscissa represents gene ratio enriched to this pathway, and the ordinate represents names of various pathways. The red represents a high degree of enrichment, and the blue represents a low degree of enrichment. A larger circle represents a large number of genes enriched in this pathway, and a smaller circle represents a small number of genes enriched in this pathway. E–H KEGG barplots (left) and bubble plots (right) of functional pathways enrichment analysis of TME stromal and immune scores-related differentially expressed genes in Caucasian (up) and Asian (down) LUAD patients. Left: KEGG barplots for KEGG functional pathway enrichment analysis of differentially expressed genes related to TME scores. The abscissa represents gene count enriched in this pathway, and the ordinate represents the names of various pathways. The red represents a high degree of enrichment, and the blue represents a low degree of enrichment. Right: KEGG bubble plots for KEGG functional pathway enrichment analysis of differentially expressed genes related to TME scores. The abscissa represents gene ratio enriched to this pathway, and the ordinate represents names of various pathways. The red represents a high degree of enrichment, and the blue represents a low degree of enrichment. A larger circle represents a large number of genes enriched in this pathway, and a smaller circle represents a small number of genes enriched in this pathway