Fig. 6

Differentially expressed genes and functional pathways enrichment analysis related to TME stromal and immune scores in Caucasian and Asian LUAD patients. A, B Deviation plot of differentially expressed genes related to TME stromal scores in Caucasian (left) and Asian (right) LUAD patients. The abscissa represents logFC values, and the ordinate represents gene names. The dark blue represents up-regulated genes in tumor tissues, and the brown represents down-regulated genes. A deviation plot is drawn based on the top 20 genes with the largest differences screened by logFC values. The abscissa represents logFC values, and the ordinate represents gene names. The dark blue represents up-regulated genes in the group with a higher TME stromal score, and the brown represents down-regulated genes. C, D GO circle plots of differentially expressed genes related to TME stromal scores in Caucasian (left) and Asian (right) LUAD patients. Five colors on the right side of the circle represent the 5 most enriched pathways, and the left coordinate represents enriched gene names and related logFC values. E, F KEGG circle plots of differentially expressed genes related to TME stromal scores in Caucasian (left) and Asian (right) LUAD patients. Five colors on the right side of the circle represent the 5 most enriched pathways, and the left coordinate represents enriched gene names and related logFC values. G, H Deviation plots of differentially expressed genes related to TME immune scores in Caucasian (left) and Asian (right) LUAD patients. The abscissa represents logFC values, and the ordinate represents gene names. The dark blue represents up-regulated genes in tumor tissues, and the brown represents down-regulated genes. Deviation plots were drawn based on the top 20 genes with the largest differences screened by logFC value. The abscissa represents logFC values, and the ordinate represents gene names. The dark blue represents up-regulated genes in the group with a higher TME immune score, and the brown represents down-regulated genes. I, J GO circle plots of differentially expressed genes related to TME immune scores in Caucasian (left) and Asian (right) LUAD patients. Five colors on the right side of the circle represent the 5 most enriched pathways, and the left coordinate represents enriched gene names and related logFC values. K, L KEGG circle plots of differentially expressed genes related to TME immune scores in Caucasian (left) and Asian (right) LUAD patients. Five colors on the right side of the circle represent the 5 most enriched pathways, and the left coordinate represents enriched gene names and related logFC values