Reproductive history and blood cell DNA methylation later in life: the Young Finns Study

Clinical Epigenetics

Table 4 Methylation sites most strongly associated with history of gestational diabetes. None meet the genome-wide significance criterion (p < 5 × 10⁻⁸)

CpG	Beta	SE	p value	chr	Gencode Basic name
cg19078878	− 0.031	0.006	1.44E − 07	chr6
cg09150251	− 0.014	0.003	8.18E − 07	chr10	RP1-251M9.2
cg02260571	− 0.010	0.002	8.35E − 07	chr2	CCDC141
cg07519259	− 0.015	0.003	9.65E − 07	chr2
cg07752304	0.004	0.001	1.12E − 06	chr19	ARID3A
cg13264059	0.007	0.001	1.62E − 06	chr10	PTPRE
cg00854172	− 0.033	0.007	2.22E − 06	chr2	AC011239.1;KLHL29
cg03987506	0.001	0.002	2.70E − 06	chr3	OXTR;CAV3
cg09228048	0.005	0.001	3.42E − 06	chr3	AC018816.4
cg11230062	− 0.018	0.004	3.44E − 06	chr1	U3
cg01150646	− 0.016	0.003	3.58E − 06	chr17
cg10556782	− 0.010	0.002	3.77E − 06	chr19	ZNF266
cg11168533	− 0.015	0.003	4.43E − 06	chr9	GNE
cg11227068	− 0.017	0.004	4.46E − 06	chr20	ROMO1; NFS1
cg19284306	− 0.022	0.005	6.00E − 06	chr1	RP1-158P9.1
cg00958475	− 0.016	0.004	6.23E − 06	chr4
cg03562652	0.010	0.002	7.40E − 06	chr2	CCDC74A
cg05164570	0.019	0.004	7.72E − 06	chr5	HARS; HARS2
cg16068780	− 0.020	0.004	8.43E − 06	chr12	SBNO1
cg10937341	− 0.011	0.002	9.63E − 06	chr9	UBE2R2

ISSN: 1868-7083