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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Alterations of DNA methylation were associated with the rapid growth of cortisol-producing adrenocortical adenoma during pregnancy

Fig. 5

DNA methylation analysis of the promoter region between non-pregnant and pregnant groups. A Schematic diagram of gene regions and CpG island region. B Bar graph showing DNA methylation in different regions between the non-pregnant and pregnant groups. C Venn diagram showing the overlap and the number of differentially methylated of the promoter region DMPs between the non-pregnant and pregnant adrenocortical adenoma patients. D, E Enriched GO and KEGG pathways (Top 30) within just the pregnant promoter hypomethylated DMPs associated genes (P < 0.05). F PPI and functional enrichment network of just pregnant promoter hypomethylated DMPs associated genes using the STRING and Cytoscape software

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