Skip to main content
Fig. 2 | Clinical Epigenetics

Fig. 2

From: Prenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals

Fig. 2

Cord blood differentially methylated regions associated with metals within the human leukocyte antigen region. Cord blood differentially methylated regions (DMRs) located within the human leukocyte antigen (HLA) region (chr6: 28,477,797–33,448,3540) were associated with prenatal exposure to a Cr in infants overall and males; b Hg in infants overall and males, and Mg in infants overall, c Cs in infants overall and males; d Cr in females; e Cs and Hg in males; f Hg and Mn in infants overall; g Cs in infants overall; h Cr in infants overall; and i Cs in infants overall. DMRs identified using comb-p (Sidak p < 0.05) adjusted for infant sex, race/ethnicity, gestational age, nulliparous, maternal age at enrollment, pre-pregnancy BMI, education, smoking, household income, and estimated cord blood cell-type proportions

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us