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Table 2 Characteristics of selected ISUS as proxies and their participation in the diagnostic models

From: Epigenetic quantification of circulating immune cells in peripheral blood of triple-negative breast cancer patients

Cell type

ISUS Probe ID

Chromosome: Positiona

Gene name

Genic region

LogReg

LogReg-VarSel

B cell

cg07721872

16:87735256

LOC100129637

Body

Yes

–

 

cg04838847

8:110587155

GOLSYN

Body

Yes

–

 

cg27565966

16:28943198

CD19

TSS200

Yes

–

Monocyte

cg23244761

6:161796850

PARK2

Body

Yes

–

 

cg05923857

10:114911615

TCF7L2

Body

Yes

–

 

cg24788483

10:114911652

TCF7L2

Body

Yes

Yes

TCD4 + 

cg05617307

10:121413182

BAG3

Body

Yes

–

 

cg14477767

4:170195438

Intergenic

–

Yes

–

 

cg20737812

15:86336631

KLHL25

5'UTR

Yes

–

TCD8 + 

cg18857618

2:87048489

CD8B

Body

Yes

–

 

cg00219921

2:87012810

CD8A

3'UTR

Yes

–

 

cg06419846

11:66083697

CD248

1stExon

Yes

Yes

Neu

cg25006077

3:152176018

MBNL1

Body

Yes

–

 

cg25739938

2:9528072

CPSF3

Body

Yes

–

 

cg05398700

14:102677141

WDR20

Body

Yes

–

NK

cg08326410

19:55314884

KIR2DL4

TSS200

Yes

Yes

 

cg23855986

11:129980502

APLP2

Body

Yes

Yes

 

cg23060465

8:141625545

EIF2C2

Body

Yes

–

Treg

cg04920616

X:49121288

FOXP3

TSS200

Yes

–

 

cg02033323

X:49005257

FOXP3

5'UTR

Yes

–

 

cg07499259

1:12188502

TNFRSF8

Body

Yes

–

  1. Neu, neutrophil; NK, natural killer cell; Treg, regulatory T cell; LogReg, logistic regression; LogReg-VarSel, variable selection in logistic regression
  2. aHuman GRCh37/hg19) Assembly