| EMPC (n = 1833) | BAA23 (n = 1977) | AS311 (n = 167) | ARIC EA (n = 1059) | ARIC AA (n = 2461) |
---|---|---|---|---|---|
Clinical trial participant | |||||
 Yes | 1833 | 1543 | 119 | – | – |
 No | 0 | 434 | 48 | – | – |
Case/control status | |||||
 Case | – | 987 | 91 | – | – |
 Control | – | 990 | 76 | – | – |
Age mean (SD) | 63.2 (7.1) | 64.6 (7.1) | 66.2 (7.2) | 59.9 (5.4) | 56.6 (5.9) |
Sex | |||||
 Female | 1833 | 1977 | 167 | 611 | 1574 |
 Male | 0 | 0 | 0 | 448 | 887 |
Ethnicity | |||||
 White | 922 | 944 | 99 | 1059 | 0 |
 African American | 474 | 631 | 49 | 0 | 2461 |
 Hispanic/Latino | 260 | 402 | 16 | 0 | 0 |
 Asian or Pacific Islander | 107 | 0 | 2 | 0 | 0 |
 American Indian or Alaskan Native | 41 | 0 | 1 | 0 | 0 |
 Other | 29 | 0 | 0 | 0 | 0 |
Smoking status | |||||
 Former and current | 853 | 913 | 99 | 610 | 1351 |
 Never | 963 | 1048 | 67 | 449 | 1110 |
Metabolic health status | |||||
 Metabolically healthy | 1254 | 1163 | 109 | 662 | 1177 |
 Metabolically unhealthy | 579 | 814 | 58 | 397 | 1284 |
BMI*Metabolic Health Z score mean (SD) | 2.96 (30.38) | 2.92 (31.59) | 2.84 (30.4) | 2.55 (29.0) | 2.82 (31.4) |
BMI mean (SD) | 29.5 (5.9) | 29.8 (6.1) | 29.3 (6.9) | 26.2 (4.3) | 30.1 (6.2) |
BMI categories | |||||
 Underweight | 7 | 13 | 0 | 20 | 18 |
 Normal | 417 | 420 | 41 | 435 | 444 |
 Overweight | 641 | 680 | 67 | 429 | 912 |
 Obese | 768 | 864 | 59 | 175 | 1087 |
Waist circumference mean (SD) | 89.5 (13.8) | 90.7 (13.7) | 89.1 (15.1) | 94.5 (12.8) | 101.4 (15.1) |
Triglycerides mean (SD) | 153 (88.2) | 146.9 (83.4) | 143.8 (82.5) | 140.4 (83.6) | 117.3 (77.7) |
HDL-cholesterol mean (SD) | 58 (15.1) | 52.1 (13.2) | 53.2 (13.0) | 52.3 (18.2) | 53.3 (17.3) |
Systolic blood pressure mean (SD) | 128 (18) | 132.1 (17.8) | 132.5 (16.6) | 118.7 (18.0) | 127.3 (20.6) |
Diastolic Blood Pressure mean (SD) | 75.3 (9.4) | 76.4 (9.3) | 76.3 (8.5) | 68.5 (9.7) | 75.2 (10.7) |
Blood glucose mean (SD) | 103 (31.1) | 108.6 (41.3) | 105.2 (37.2) | 105.9 (28.6) | 129.3 (64.3) |