Skip to main content

Table 1 Initial and final numbers of CpGs for each DNAm model of smoking

From: Epigenetic modelling of former, current and never smokers

Classes Model name Novel/literature Number of supplied features to LASSO (CpGs) Final number of features (CpGs)
“Ever” versus never AHRR Literature NA 1
  Maas Literature NA 13
  Agnostic LASSO Novel 450K 29
  Candidate CpG LASSO Novel 14 9
Current versus former AHRR Literature NA 1
  Maas Literature NA 13
  Agnostic LASSO Novel 450K 20
  Candidate CpG LASSO Novel 40 4
  1. “Literature”-based models contain pre-specified CpG sites and betas and were therefore not supplied to LASSO models in this paper. “Novel” models denote models where we supplied sets of CpGs for feature selection via cross-validated LASSO. The “final number of features” are those used to create the various DNAm scores of smoking seen in this paper