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Fig. 3 | Clinical Epigenetics

Fig. 3

From: DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status

Fig. 3

Density plots, volcano plots and Venn diagrams to compare beta values, differentially methylated positions (DMP) and differentially methylated regions (DMR) between triple negative breast cancers (n = 14) and the two subtypes with low hormone receptor expression (LowHR; n = 23). ac Density plots showing the pairwise correlation of beta values of all CpGs between the three subgroups. df Volcano plots visualizing DMPs between LowHR HRpos-like and TNBC samples (d), LowHR HRpos-like and LowHR TNBC-like specimens (e) as well as TNBC and LowHR TNBC-like samples (f). f Venn diagrams showing overlapping and unique DMPs and DMRs between the pairwise comparisons

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