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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Histone H3 lysine 27 acetylation profile undergoes two global shifts in undernourished children and suggests altered one-carbon metabolism

Fig. 4

Functional annotation of genes associated with significantly downregulated H3K27ac regions in 1-year-old stunted children. a Genome browser screenshot showing a representative region in 1-year-old children in which read coverage decreased with decreasing ΔHAZ (1 year) score, i.e. H3K27ac was lower in stunted children. Track colors correspond to the child’s ΔHAZ (1 year) score. Genes associated with the region are labeled. b Network of biological terms as in Fig. 3b applied on data from 1-year-old children. c Genes from highlighted biological terms in b are shown in a pathway diagram. PPP pentose phosphate pathway, SSP serine synthesis pathway

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Clinical Epigenetics

ISSN: 1868-7083

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