Skip to main content
Fig. 2 | Clinical Epigenetics

Fig. 2

From: Hi-C profiling of cancer spheroids identifies 3D-growth-specific chromatin interactions in breast cancer endocrine resistance

Fig. 2

Identifying the differential TADs between 2D monolayers and 3D spheroids. A Bar graph depicting the number of the TADs, Boundaries, and Gaps were identified for MCF10A_2/3D, MCF7_2D/3D and MCF7TR_2D/3D, respectively. B The distribution of TAD size showing there is no significant difference between MCF10A_2D/3D, MCF7_2D/3D and MF7TR_2D/3D, respectively. C Doughnut chart showing a percentage breakdown for TAD changes between 2D and 3D conditions for three cell types respectively. D Screenshots demonstrating two types of TAD change, Del and Neo. Region Chr1: 152.00–152.44 Mb (left panel) and Chr2:238.00–238.48 Mb (right panel)

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us