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Table 1 Clinicopathological features stratified by QMSP

From: Impact of molecular surgical margin analysis on the prediction of pancreatic cancer recurrences after pancreaticoduodenectomy

Valiables

All (n = 38)

Molecular surgical margin analysis

Negative (n = 21)

Positive (n = 17)

p value

Age, years

Median (range)

66 (36–86)

64 (36–86

72 (49–82)

0.735

Sex, n (%)

Female

13 (34.2)

7 (33.3)

6 (35.3)

1

Male

25 (65.8)

14 (66.7)

11 (64.7)

Tumor size, cm

Median (range)

2.3 (0.9–4.3)

2.5 (0.9–3.5)

2.1 (1.0–4.3)

0.401

Initial resectability, n (%)

Resectable

16

6

10

0.133

Borderline resectable

15

11

4

Unresectable

7

4

3

 

NAT, n (%)

Yes

24 (63.2)

17 (81.0)

7 (41.2)

0.019

No

14 (36.8)

4 (19.0)

10 (58.8)

Radiation, n (%)

Yes

3 (7.9)

3 (14.3)

0 (0)

0.238

No

35 (92.1)

18 (85.7)

17 (100)

CA19-9, U/ml

Median (range)

51.5 (1–5790

51 (1–5790

53 (1–1020)

0.871

DUPAN-2, U/ml

Median (range)

61.5 (25–1000)

47 (25–590)

120 (25–1000)

0.121

Pathological surgical margin, n (%)

Positive

11 (28.9)

6 (28.6)

5 (29.4)

1

Negative

27 (71.1)

15 (71.4)

12 (70.6)

Pathological surgical margin, μm

Median (range)

829 (0–4000)

1081 (0–4000)

372 (0–2648)

0.521

CY, n (%)

Positive

3 (7.9)

1 (4.8)

2 (11.8)

0.577

Negative

35 (92.1)

20 (95.2)

15 (88.2)

n, n (%)

Positive

6 (15.8)

5 (23.8)

1 (5.9)

0.197

Negative

32 (84.2)

16 (76.2)

16 (94.1)

ly, n (%)

Positive

23 (60.5)

12 (57.1)

11 (64.7)

0.744

Negative

15 (39.5)

9 (42.9)

6 (35.3)

v, n (%)

Positive

16 (42.1)

7 (33.3)

9 (52.9)

0.324

Negative

22 (57.9)

14 (66.7)

8 (47.1)

s, n (%)

Positive

29 (76.3)

16 (76.2)

13 (76.5)

1

Negative

9 (23.7)

5 (23.8)

4 (23.5)

rp, n (%)

Positive

29 (76.3)

15 (71.4)

14 (82.4)

0.476

Negative

9 (23.7)

6 (28.6)

3 (17.6)

ch, n (%)

Positive

12 (31.6)

6 (28.6)

6 (25.3)

0.734

Negative

26 (68.4)

15 (71.4)

11 (64.7)

du, n (%)

Positive

15 (39.5)

7 (33.3)

8 (47.1)

0.509

Negative

23 (60.5)

14 (66.7)

9 (52.9)

pv, n (%)

Positive

12 (31.6)

7 (33.3)

5 (29.4)

1

Negative

26 (68.4)

14 (66.7)

12 (70.6)

  1. Bold indicates P < 0.05
  2. NAT; neoadjuvant chemotherapy, CY; Peritoneal washing cytology, n; Lymph node metastasis, ly; Lymphatic invasion, v; Venous invasion, s; Serosal side of the anterior pancreatic invasion, rp; Retropancreatic tissue invasion, ch; Bile duct invasion, du; Duodenal invasion, pv; Portal vein system invasion