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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals

Fig. 2

Genome-wide mirror Manhattan plot of association statistics from epigenome-wide association analysis in multi-ethnic Asians with BMI association results on the upper panel and WC association results on the lower panel. At an epigenome-wide significance of PFDR < 0.05, we identified 116 BMI-associated and 8 WC-associated CpGs. Novel associations were labeled with the nearest candidate gene and colored by trait. Novel CpGs near THADA, TNIK, LINCO1449, and BIRC3 were associated with BMI only, while CpGs near ETAA1 and RSRC1 were associated with both BMI and WC

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