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Table 1 Characteristics of the study samples

From: Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation

 

Betamethasone administration group (BET group, n = 52)

Control group (n = 84)

p valuea

Mean age of pregnant person in years (SD)

28.46 (6.24)

29.60 (5.51)

0.28

Ethnicity non-European (%)

3 (5.8%)

7 (8.3%)

1.00

Smoking during pregnancy (% yes)

14 (26.92%)

18 (21.42%)

0.60

Mean BMI before pregnancy (SD)

24.30 (5.17)

23.81 (4.21)

0.58

Mean time between BET administration and birth in days (SD)

67.38 (29.87) up to 7 days: 1 7–28 days: 4 28–56 days: 14 over 56 days: 33

NA

NA

Mean gestational age at birth in weeks (SD)

38.03 (2.10)

38.23 (1.88)

0.56

Preterm birth (before week 37)

17 (32.69%)

17 (20.42%)

0.15

Delivery mode: C-section

11 (21.15%)

24 (28.57%)

0.44

Labor

49 (94.23%)

72 (85.71%)

0.21

Parity

1.65 (1.02)

1.97 (1.41)

0.13

Birth weight in grams

3069 (539)

3198 (436)

0.15

Sex (% male)

24 (46.15%)

46 (54.76%)

0.42

  1. The table refers to samples which provide information on phenotypes and methylation levels
  2. SD standard deviation
  3. aNominal p value from Chi-square test (categorical variables) or t test (quantitative variables)