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Fig. 5 | Clinical Epigenetics

Fig. 5

From: DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A2 in human vulnerable atherosclerotic plaque

Fig. 5

Top 20 vulnerability-specific hypomethylated genes with increased expression and their biological process. a The top 20 genes that were hypomethylated in SYM plaques and showing an increased expression in both advanced plaques and macrophages from ruptured plaques. These genes are presented in graph descending according to the log10 (p values). b Biological process GO terms of the top 20 genes. PLA2G7 is highlighted with a red box. SYM, symptomatic; and GO, gene ontology

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