Table 3 Top biological processes and KEEG pathway connected to the PWS DMRs
Biological process/KEGG pathway | GO/KEGG ID | Adjusted_p_value |
|---|---|---|
Nervous system development | GO:0007399 | 1.23E−14 |
Generation of neurons | GO:0048699 | 1.30E−13 |
Neurogenesis | GO:0022008 | 1.71E−13 |
Anatomical structure development | GO:0048856 | 1.16E−12 |
Synapse | GO:0045202 | 1.51E−11 |
Aldosterone synthesis and secretion | KEGG:04925 | 2.54E−03 |
Cushing syndrome | KEGG:04934 | 5.01E−03 |
Cortisol synthesis and secretion | KEGG:04927 | 9.20E−03 |
Cholinergic synapse | KEGG:04725 | 1.00E−02 |
Oxytocin signaling pathway | KEGG:04921 | 1.39E−02 |
Endocrine resistance | KEGG:01522 | 1.54E−02 |