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Table 1 Study population characteristics

From: A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease

 

Mean

(Minimum/maximum)

Age (years)

43 ± 0.45

(18–74)

Weight (kg)

110.7 ± 0.8

(65.8–226.6)

Height (m)

1.68 ± 0.003

(1.47–2.06)

BMI (kg/m2)

38.8 ± 0.22

(24.97–69.13)

Waist circumference (cm)

116.7 ± 0.5

(83.5–193)

Hip circumference (cm)

122.2 ± 0.4

(95–160)

Waist-to-hip ratio

0.96 ± 0.004

(0.66–1.35)

Fat free mass (kg)

56.2 ± 0.4

(36.5–110)

Fat mass (kg)

54.3 ± 0.5

(16.9–134.5)

Fat mass (%)

48.87 ± 0.27

(22.3–65.3)

Total abdominal adipose tissue (cm2)

799.5 ± 6.6

(246–1386)

Visceral abdominal tissue (cm2)

195.9 ± 3.2

(29–567)

Subcutaneous abdominal tissue (cm2)

603.6 ± 5.6

(166–1059)

Systolic blood pressure (mmHg)

127.1 ± 0.5

(90–180)

Diastolic blood pressure (mmHg)

75.45 ± 0.37

(49–115)

Creatinine kinase (mg/dL)

0.81 ± 0.006

(0.38–1.64)

Aspartate aminotransferase (U/L)

23.6 ± 0.5

(7–133)

Alanine aminotransferase (U/L)

35.8 ± 0.8

(7–265)

Alkaline phosphatase (U/L)

79.94 ± 0.79

(30–236.03)

gamma-glutamyltransferase (U/L)

43.43 ± 1.19

(11.79–315.16)

Total cholesterol (mg/dL)

199 ± 1.40

(75–400.44)

High-density-lipoprotein Cholesterol (mg/dL)

50.83 ± 0.49

(24–107.17)

Triglycerides (mg/dL)

152.97 ± 2.93

(17–823.01)

Low-density-lipoprotein cholesterol (mg/dL)

117.81 ± 1.24

(17.6–294.76)

Insulin resistance (HOMA)

4.27 ± 0.23

(0.07–147.65)

Steatosis (0:1:2:3)

109:151:119:82

 

Ballooning (0:1:2)

139:187:135

 

Lobular inflammation (0:1:2:3)

148:208:75:30

 

Fibrosis stage (0:1:2:3:4)

287:91:51:28:3

 

Adjusted SAF activity (0:1:2:3:4:5)

100:71:112:118:44:16

 

NAFLD activity score (0:1:2:3:4:5:6:7:8)

75:44:48:62:84:60:50:30:8

 

NAFLD staging (1:2:3:4)

61:80:210:53

 
  1. Patient clinical and biochemical variable statistics are represented for the complete HEPADIP cohort (Ntotal = 790; 565 females—225 males). Values are expressed as the mean ± standard error of the mean. Lower and upper limits are indicated as minimum/maximum. The distribution of patients (x:y:z) according to the histological characteristics (Nliver biopsy = 461) are shown as absolute values. The histological criteria were evaluated by the NASH-CRN scoring system