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Fig. 5 | Clinical Epigenetics

Fig. 5

From: A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease

Fig. 5

Genomic distribution of regulatory polymorphism rs705379:C > T in relation to histological liver features. The association of liver histology parameters hepatocellular ballooning (a), lobular inflammation (b), adjusted SAF activity (c), and NAFLD staging (d) with common SNP rs705379:C > T is shown in a population of patients with a wide range of (hepato)metabolic derangements. The different categories of each histological liver feature are represented on the x-axis. The distribution of each genotype in the HEPADIP population is exposed as a percentage on the y-axis. Light grey to black shading represents respectively genotypes TT, CT, CC

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