Skip to main content

Table 2 Overview of the effect of polymorphism and BDNF promoter Ib methylation on reward bias analysed using repeated measures ANOVA

From: Interplay of Val66Met and BDNF methylation: effect on reward learning and cognitive performance in major depression

 

Both groups

Depressed group

Control group

F

p

ηp2

F

p

ηp2

F

p

ηp2

Univariate models

Block*SNP

1.843

0.163

0.015

3.061

 < 0.05

0.040

0.089

0.915

0.002

Block*Promoter Ib DNAm

3.804

0.026

0.030

3.301

0.040

0.044

0.471

0.626

0.009

Multivariate model

Block*SNP

1.592

0.207

0.013

2.675

0.072

0.036

0.132

0.876

0.003

Block*Promoter Ib DNAm

3.656

0.030

0.029

3.126

0.047

0.042

0.508

0.603

0.010

Interaction

Block*SNP

0.413

0.650

0.003

2.641

0.075

0.036

1.668

0.194

0.034

Block*Promoter Ib DNAm

3.529

0.034

0.028

3.101

0.048

0.042

0.525

0.593

0.011

Block*SNP*Promoter Ib DNAm

0.131

0.865

0.001

1.635

0.199

0.023

1.608

0.206

0.032

  1. Significant predictors are marked in bold
Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us