Fig. 4

ROC curves representing the logistic models to identify higher CRC risk patients. MOD1 is the logistic model without the methylation parameter, while MOD2 comprises the methylation value. Black curves show the efficiency of the models built using the current parameters, while gray curves display the efficiency of the new models comprising the methylation level. a All adenomas of the study were evaluated. b The subset consisting only of tubular adenomas was considered. c The subset including only the controls with at least 5 years of follow-up and the cases that had developed CRC within 10 years was assessed