Table 3 Predicted and observed methylation levels for XY, XXY, XXXY, and XXXXY at the MAOA and AR loci
From: DNA methylation and behavioral dysfunction in males with 47,XXY and 49,XXXXY: a pilot study
| Â | XY | XXY | XXXY* | XXXXY | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Xa/Obs | Xa | Xi | Obs | XaXaXa | XaXaXi | XaXiXi | XiXiXi | Obs | XaXaXaXa | XaXaXaXi | XaXaXiXi | XaXiXiXi | XiXiXiXi | Obs |
MAOA | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CpG-1 | 10.4 | 10.4 | 56.4 | 33.4 | 10.4 | 25.8 | 41.1 | 56.4 | 47.2 | 10.4 | 21.9 | 33.4 | 44.9 | 56.4 | 54.3 |
CpG-2 | 6.9 | 6.9 | 98.1 | 52.5 | 6.9 | 37.3 | 67.7 | 98.1 | 68.4 | 6.9 | 29.7 | 52.5 | 75.3 | 98.1 | 70.8 |
CpG-3 | 5.6 | 5.6 | 45.9 | 25.7 | 5.6 | 19.0 | 32.5 | 45.9 | 39.6 | 5.6 | 15.7 | 25.7 | 35.8 | 45.9 | 41.2 |
CpG-4 | 5.9 | 5.9 | 91.8 | 48.9 | 5.9 | 34.6 | 63.2 | 91.8 | 59.9 | 5.9 | 27.4 | 48.9 | 70.3 | 91.8 | 63.1 |
CpG-5 | 6.0 | 6.0 | 83.0 | 44.5 | 6.0 | 31.7 | 57.3 | 83.0 | 61 | 6.0 | 25.2 | 44.5 | 63.7 | 83.0 | 69.0 |
CpG-6 | 4.2 | 4.2 | 77.5 | 40.9 | 4.2 | 28.7 | 53.1 | 77.5 | 53.0 | 4.2 | 22.5 | 40.9 | 59.2 | 77.5 | 62.0 |
CpG-7 | 7.6 | 7.6 | 98.1 | 52.9 | 7.6 | 37.8 | 67.9 | 98.1 | 72.2 | 7.6 | 30.2 | 52.9 | 75.5 | 98.1 | 78.3 |
AR | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CpG-1 | 3.0 | 3.0 | 34.2 | 18.6 | NA | NA | NA | NA | NA | 3.0 | 10.8 | 18.6 | 26.4 | 34.2 | 31.0 |
CpG-2 | 4.6 | 4.6 | 37.1 | 20.8 | NA | NA | NA | NA | NA | 4.6 | 12.7 | 20.8 | 28.9 | 37.1 | 28.4 |
CpG-3 | 7.1 | 7.1 | 82.7 | 44.9 | NA | NA | NA | NA | NA | 7.1 | 26.0 | 44.9 | 63.8 | 82.7 | 54.9 |
CpG-4 | 10.7 | 10.7 | 38.6 | 24.7 | NA | NA | NA | NA | NA | 10.7 | 17.7 | 24.7 | 31.6 | 38.6 | 36.5 |