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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Current understanding of epigenetics mechanism as a novel target in reducing cancer stem cells resistance

Fig. 1

Proposed models for cancer stem cells (CSCs) origin in cancer development. In the normal differentiation process, a cell differentiates to form two cells, differentiated and primitive. A finally differentiated cell is formed from precursor progenitor cell and eventually subject to apoptosis. CSC may originate from a normal stem cell, a normal progenitor cell, or a normal differentiated cell by genetic mutation which will activate self-renewal genes in them. Also cancer cells via EMT can change to CSCs

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Clinical Epigenetics

ISSN: 1868-7083

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