Fig. 6
From: Increased PARylation impacts the DNA methylation process in type 2 diabetes mellitus
Methylation and hydroxymethylation status of SOCS3 CpG 14 and 16 in low and high PAR T2DM patients and in control individuals. Percentage of methylated (5mC), hydroxymethylated (5hmC) and unmethylated (C) cytosine as detected by methylation-sensitive PCR. Data are mean ± SD. Statistically significant differences as detected by ANOVA followed by the Bonferroni post-hoc test are indicated by the asterisks. *p ≤ 0.05, **p ≤ 0.01. N = 10 CT, 10 low PAR, 10 high PAR