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Table 2 Detection of methylation markers, cg054 and SCG3, by TAM-MSP in plasma

From: Methylated markers accurately distinguish primary central nervous system lymphomas (PCNSL) from other CNS tumors

ID Diagnosis cg054/ACTB copies SCG3/ACTB copies cg054 MAF (%) SCG3 MAF (%) Total MAF (%)
PCNSL_1 PCNSL 1/660 0/660 0.20 0.00 0.20
PCNSL_2 PCNSL 8/1867 15/1867 0.45 0.80 1.25
PCNSL_3 PCNSL 84/2496 79/2496 3.37 3.15 6.52
PCNSL_4 PCNSL 9/2071 32/2071 0.42 1.55 1.97
PCNSL_5 PCNSL 1408/2826 1127/2826 49.82 39.88 89.69
PCNSL_6 PCNSL 0/2131 0/2131 0.00 0.00 0.00
PCNSL_7 PCNSL 0/1536 0/1536 0.00 0.00 0.00
PCNSL_8 PCNSL 0/243 0/243 0.00 0.00 0.00
PCNSL_9 PCNSL 54/5158 0/5158 1.04 0.00 1.04
PCNSL_10 PCNSL 21/2051 0/2051 1.03 0.00 1.03
PCNSL_11 PCNSL 0/76 0/76 0.00 0.00 0.00
PCNSL_12 PCNSL 0/7829 0/7829 0.00 0.00 0.00
PCNSL_13 PCNSL 0/1744 0/1744 0.00 0.00 0.00
PCNSL_14 PCNSL 2/1846 0/1846 0.09 0.00 0.09
PCNSL_15 PCNSL 0/37 0/37 0.00 0.00 0.00
Other_1 GBM 2/1279 0/1279 0.14 0.00 0.14
Other_2 IGa 6/2468 40/2468 0.24 1.61 1.85
Other_3 GBM 0/687 0/687 0.00 0.00 0.00
Other_4 GBM 13/115 0/1115 1.18 0.00 1.18
Other_5 DMG 0/1093 0/1093 0.00 0.00 0.00
Healthy_1 NA 0/1756 4/1756 0.02 0.24 0.26
Healthy_2 NA 0/2099 16/2099 0.00 0.76 0.76
Healthy_3 NA 0/2414 0/2414 0.00 0.00 0.00
Healthy_4 NA 0/1373 19/1373 0.00 1.37 1.37
Healthy_5 NA 0/1529 0/1529 0.00 0.00 0.00
Healthy_6 NA 0/1307 0/1307 0.00 0.00 0.00
  1. PCNSL primary central nervous system lymphoma, MAF methylation allele frequency, other CNS tumors, GBM glioblastoma multiformae, DMG diffuse midline glioma, IG infiltrating glioma
  2. aH3-K27M mutation