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Table 1 Participant group characteristics, per comparison

From: Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease: an exploratory study

  Analysis 1* Analysis 2 Analysis 3* Analysis 4
Cases     
Number of participants 107 107 73 73
Diagnosis T1DM with ESKD (transplant recipients or dialysis) T1DM with ESKD (transplant recipients or dialysis) T1DM with ESKD (transplant recipients only) T1DM with ESKD (transplant recipients only)
Number of F:M 43:64 43:64 26:47 26:47
Average Age (St. Dev.) 41.7 years (9.7) 41.7 years (9.7) 40.5 years (9.3) 40.5 years (9.3)
Average duration of T1DM (St. Dev.) 29.1 years (6.5) 29.1 years (6.5) 30.1 years (5.7) 30.1 years (5.7)
Controls     
Number of participants 107 253 73 253
Diagnosis Long-duration of T1DM with no evidence of kidney disease Long-duration of T1DM with no evidence of kidney disease Long-duration of T1DM with no evidence of kidney disease Long-duration of T1DM with no evidence of kidney disease
Number of F:M 43:64 121:132 26:47 121:132
Average Age (St. Dev.) 41.2 years (10.2) 41.2 years (9.6) 40.1 years (9.1) 41.2 years (9.6)
Average duration of T1DM (St. Dev.) 26.8 years (7.9) 26.3 years (7.4) 25.5 years (7.8) 26.3 years (7.4)
  1. ESKD end-stage kidney disease, F females, M males, St. Dev. standard deviation, T1DM type 1 diabetes
  2. *Analyses 1 and 3: Matched cases and controls for sex, average age (≤ 5 years) and duration of diabetes (≤ 10 years)