Table 3 circRNAs involved in diabetes-related renal inflammation and fibrogenesis
CircRNAs | Experimental models | Functions involved | Axis | Ref |
|---|---|---|---|---|
circRNA_15698 | T2DN, Diabetic db/db mice | ECM accumulation | circRNA_15698/miR-185/TGF‐β1 axis | [132] |
circRNA-0080425 | T1DN, STZ-induced mice | renal fibrosis | circRNA-0080425/miR‐24‐3p/FGF11 axis | [133] |
circ-LRP6 | Not mentioned, mesangial cells | renal inflammation and fibrosis | circLRP6/miR‐205/HMGB1 axis | [134] |
circ-WBSCR17 | T1DN, STZ-induced mice | inflammatory responses and fibrosis | circ-WBSCR17/miR-185-5p/SOX6 axis | [135] |
circ-RNF169 | Not mentioned, glomerular endothelial cells | cell proliferation and EMT | Unknown | [136] |
circSTRN3 | Not mentioned, glomerular endothelial cells | cell proliferation and EMT | Unknown | [136] |