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Table 1 Descriptive characteristics of the Framingham Offspring Study participants included in this integration analysis

From: DNA methylation and gene expression integration in cardiovascular disease

Variable

Methylation

Gene expression

n = 2055

n = 914

Agea

65.23 (8.59)

64.48 (8.43)

Sex, male, n (%)

871 (42.38)

336 (36.76)

Total cholesterol, mg/dLa

190.16 (35.79)

192.30 (35.62)

HDL-C, mg/dLa,c

58.91 (18.45)

59.51 (17.96)

Triglycerides, mg/dLb,c

100 (73,138)

101 (73,140.75)

SBP, mmHga,c

125.19 (16.83)

125.35 (16.97)

DBP, mmHga,c

72.31 (9.90)

72.65 (10.16)

Glucose, mg/dLb

101 (94,109)

100 (93,108)

Smokers, n (%)

199 (9.68)

96 (10.50)

BMI, kg/m2a,c

27.99 (5.30)

27.88 (5.33)

Waist, cma,c

100.56 (14.47)

100.08 (14.67)

CHD, n (%)

83 (4.04)

28 (3.06)

CVD, n (%)

201 (9.78)

79 (8.64)

  1. SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, Waist waist circumference, CHD coronary heart disease, CVD cardiovascular disease
  2. aMean (standard deviation)
  3. bMedian (interquartile range)
  4. cHDL-C, high-density lipoprotein cholesterol