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Fig. 7 | Clinical Epigenetics

Fig. 7

From: The impact of CBP expression in estrogen receptor-positive breast cancer

Fig. 7

CREBBP and KAT2A gene amplification in breast cancer cases with different ERĪ± and PR status. a Bars depict the association of CREBBP and KAT2A genes amplification (AMP) across different breast cancer subtypes (Luminal B: ERĪ±+/HER2+-high proliferation, Luminal A: ERĪ±+/HER2+-low proliferation, Triple negative: ERĪ±āˆ’/HER2āˆ’ and HER2-overexpressed: HER2+). b, c The amplification status of CREBBP and KAT2A genes are depicted for b ERĪ±+ā€‰(green) and ERĪ±āˆ’ (orange) samples and for c PR+ (green) and PRāˆ’ (orange) samples. d The distribution of breast cancer patients who received hormonal therapy according to their CREBBP and KAT2A gene amplification status. pā€‰<ā€‰0.05 is statistically significant

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