Skip to main content

Table 4 44 CpGs associated with AGA vs. SGA when treats birthweight as categorical variable. The coefficient estimates are the difference in % of methylation per AGA vs. SGA. In bold the CpG with the strongest effect

From: Birthweight DNA methylation signatures in infant saliva

CpG Chromosome Gene allocation or nearest gene Effect estimate Standard error Nominal p-value FDR corrected p-value
cg26168577 17 MRC2 1.374 2.17E−03 5.36E−09 0.002
cg03066788 8 PNOC − 2.371 3.92E−03 2.07E−08 0.004
cg26615232 1 USH2A − 1.304 2.31E−03 1.3E−07 0.017
cg12055114 19 LMNB2 0.898 1.62E−03 2.18E−07 0.017
cg04873627 4 TBC1D19 1.771 3.20E−03 2.3E−07 0.017
cg15225594 5 20 kb down ERCC8 2.016 3.68E−03 2.76E−07 0.017
cg01286950 2 AFF3 − 0.747 1.37E−03 3.4E−07 0.017
cg18072629 10 GATA3-AS1 0.715 1.32E−03 3.62E−07 0.017
cg13984701 9 COL5A1 4.051 7.49E−03 3.88E−07 0.017
cg26332310 1 BARHL2 − 1.867 3.47E−03 4.39E−07 0.017
cg24391471 3 ZDHHC3 − 0.829 1.55E−03 4.84E−07 0.017
cg02547025 2 LBH − 0.517 9.69E−03 5.26E−07 0.017
cg23508813 3 2.5 kb down LOC100507274 2.372 4.45E−03 5.33E−07 0.017
cg26589351 17 SPOP − 1.370 2.58E−03 5.97E−07 0.018
cg06234201 16 DUS2 2.202 4.16E−03 6.49E−07 0.018
cg23954819 12 BRI3BP − 2.136 4.06E−03 7.26E−07 0.019
cg19445996 17 RAB37 − 0.744 1.42E−03 7.85E−07 0.019
cg02980127 14 14,5 kb down ENSG00000258736.1 1.402 2.70E−03 9.4E−07 0.022
cg22869025 20 ACSS1 0.629 1.22E−03 1.14E−06 0.025
cg19403534 10 PRLHR 1.688 3.28E−03 1.22E−06 0.025
cg12322146 3 125 kb down RBMS3 4.106 8.01E−03 1.31E−06 0.025
cg06458489 5 150 kb down SNORA63 − 0.999 1.95E−03 1.38E−06 0.025
cg00383136 6 HLA-DRA 1.370 2.68E−03 1.39E−06 0.025
cg16899265 18 GRP − 1.257 2.47E−03 1.59E−06 0.027
cg15847996 10 INPP5A 2.390 4.71E−03 1.61E−06 0.027
cg08715720 5 PPP2R2B 0.780 1.55E−03 1.83E−06 0.030
cg20388707 2 NGEF 1.510 3.03E−03 2.31E−06 0.036
cg01504555 16 SYCE1L − 0.766 1.54E−03 2.4E−06 0.036
cg07965823 14 ISM2 − 0.820 1.65E−03 2.64E−06 0.036
cg20244295 15 ZNF710 1.049 2.12E−03 2.65E−06 0.036
cg09311778 17 2 kb down KAT7 − 0.795 1.61E−03 2.78E−06 0.036
cg05754929 16 GSE1 − 1.993 4.03E−03 2.81E−06 0.036
cg18246134 3 LINC02877 − 0.767 1.55E−03 2.85E−06 0.036
cg21688288 21 PDE9A 1.994 4.05E−03 3.08E−06 0.038
cg22159939 1 30 kb down CENPF − 1.137 2.32E−03 3.49E−06 0.042
cg25271404 15 GOLGA8B − 0.617 1.26E−03 3.62E−06 0.042
cg24745895 7 5 kb up AKR1D1 0.669 1.38E−03 4.01E−06 0.044
cg17836487 2 TMEM131 − 1.328 2.73E−03 4.07E−06 0.044
cg24113784 17 MIEF2 1.050 2.16E−03 4.08E−06 0.044
cg00701706 17 OTOP3 − 1.747 3.62E−03 4.57E−06 0.048
cg24663455 10 50,5 kb down MGMT − 1.615 3.35E−03 4.73E−06 0.048
cg08935613 11 HYLS1 − 0.720 1.50E−03 4.83E−06 0.048
cg22213242 11 CD248 1.191 2.48E−03 4.91E−06 0.048
cg24420742 12 NAV3 1.994 4.15E−03 4.96E−06 0.048