Fig. 4

EZH2 mutations and chromosome 7 aberrations are associated with inferior OS in AML patients. a OS of AML patients by EZH2 mutation status. 21 patients in the EZH2-wt and one patient in the EZH2-mut group were censored (still alive at last follow-up). b The presence of an EZH2 mutation is associated with inferior OS in the subgroup of AML patients having received intensive therapy. 21 patients in the EZH2-wt and one patient in the EZH2-mut group were censored (still alive at last follow-up). c In AML patients having received non-intensive therapy, OS is similar in EZH2-mut and EZH2-wt patients. d OS of AML patients by chromosome 7 status. 21 patients without chromosome 7 abnormalities and one patient with del(7q)/-7 were censored (still alive at last follow-up). e OS of AML patients by EZH2 mutation status excluding patients with chromosome (chr.) 7 aberrations. 20 patients in the EZH2-wt and one patient in the EZH2-mut group were censored (still alive at last follow-up)