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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Epigenetic evidence of an Ac/Dc axis by VPA and SAHA

Fig. 4

Differential histone modification at the transcription start site associated with gene expression. Correlations are shown for VPA- and SAHA-stimulated cells showing increased (a, c) and reduced (b, d) gene expression associated with the histone modifications, H3K9/14ac, H3K4me3 and H3K9me3. Genes are grouped (x-axis) according to increased or reduced expression derived from RNA-seq and shown as a commutative rank (i.e. top 10 genes, top 20 genes, top 40 genes, and so on), with “nc” representing no change (P < 0.05). Correlations are shown as the percentage of genes in each rank associated with changes in histone modification within 5-kb window of the transcriptional start site

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Clinical Epigenetics

ISSN: 1868-7083

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