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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Differential methylation EPIC analysis discloses cisplatin-resistance related hypermethylation and tumor-specific heterogeneity within matched primary and metastatic testicular germ cell tumor patient tissue samples

Fig. 6

Scatterplot of the of the mean beta values (a) and volcano plot of the pairwise comparison (b) related to differential methylation among embryonal carcinoma patients with different outcome and response to cisplatin, at the promoter level. In the scatterplot, the transparency corresponds to point density. Blue points represent differentially methylated sites (according to the combined rank criteria, see Methods). Red dots represent the 1000 best ranking sites. In the volcano plot, dots are colored according to combined rank, and the yy axis represents the combined p values of a given site. CispR cisplatin resistant behavior, CispS cisplatin sensitive behavior

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Clinical Epigenetics

ISSN: 1868-7083

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