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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Differential methylation EPIC analysis discloses cisplatin-resistance related hypermethylation and tumor-specific heterogeneity within matched primary and metastatic testicular germ cell tumor patient tissue samples

Fig. 2

Unsupervised hierarchical clustering of samples based on all methylation values at CpG site (a) and promoter (b) level. The heatmap displays only selected sites/regions with the highest variance across all samples. Notice distinct clustering of samples from patient #1. Also, notice higher methylation density represented by higher beta values at certain CpG sites (upper right corner) and promoters (lower right corner) for patient #3 compared to patient #4 samples. For CpG site clustering, CGI relation is given on the left side of the heatmap

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Clinical Epigenetics

ISSN: 1868-7083

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