|
Age years, mean ± SD
|
73.50 ± 5.72
| | | |
|
Sex
|
|
Female
|
14 (87.5%)
| | | |
|
Male
|
2 (12.5%)
| | | |
|
Body Measures, mean ± SD
|
|
Weight (kg)
|
95.7 ± 21.3
|
91.5 ± 22.1
|
− 4.2 ± 3.7
|
< 0.001
|
|
Body Mass Index (kg/m2)
|
36.2 ± 7.0
|
34.6 ± 7.4
|
− 1.6 ± 1.4
|
< 0.001
|
|
Fat Mass (%)
|
49.0 ± 5.0
|
48.0 ± 5.5
|
− 0.9 ± 2.4
|
0.13
|
|
Visceral Fat mass, (L)
|
4.0 ± 1.8
|
3.6 ± 2.2
|
− 0.4 ± 1.0
|
0.15
|
|
Skeletal muscle mass (kg)
|
48.8 ± 15.9
|
47.5 ± 15.0
|
− 1.3 ± 2.3
|
0.04
|
|
Appendicular lean mass (kg)
|
12.3 ± 4.0
|
12.1 ± 3.8
|
− 0.3 ± 0.7
|
0.11
|
|
Functional measures, mean ± SD
|
|
Grip strength (kg)
|
18.7 ± 5.9
|
21.9 ± 6.6
|
3.2 ± 4.1
|
0.008
|
|
Gait speed (sec)
|
1.1 ± 0.3
|
1.1 ± 0.25
|
0.02 ± 0.2
|
0.69
|
|
Sit-to-stand (sec)
|
10.0 ± 2.7
|
7.6 ± 1.8
|
− 2.4 ± 2.2
|
< 0.001
|
|
Six-minute walk (m)
|
406.4 ± 101.1
|
448.6 ± 82.12
|
29.3 ± 34.6
|
0.006
|
|
Immune Cell Proportions, mean ± SD
|
|
CD8T
|
0.06 ± 0.02
|
0.06 ± 0.02
|
0.00 ± 0.01
|
0.16
|
|
CD4T
|
0.18 ± 0.03
|
0.18 ± 0.03
|
− 0.00 ± 0.02
|
0.81
|
|
Natural Killer Cells
|
0.05 ± 0.02
|
0.05 ± 0.02
|
0.00 ± 0.01
|
0.4
|
|
B Cells
|
0.05 ± 0.02
|
0.05 ± 0.02
|
− 0.00 ± 0.01
|
0.76
|
|
Monocyte
|
0.08 ± 0.02
|
0.07 ± 0.02
|
− 0.00 ± 0.01
|
0.06
|
|
Neutrophils
|
0.62 ± 0.05
|
0.62 ± 0.05
|
− 0.00 ± 0.03
|
0.97
|
|
Methylation age clocks, mean ± SD
|
|
Hannum
|
79.4 ± 6.8
|
78.6 ± 6.6
|
− 0.8 ± 4.8
|
0.51
|
|
Horvath
|
79.3 ± 6.8
|
78.2 ± 6.4
|
− 1.1 ± 2.8
|
0.14
|
|
PhenoAge
|
62.7 ± 6.4
|
62.3 ± 7.0
|
− 0.5 ± 4.1
|
0.64
|
