Table 1 Extrinsic epigenetic age acceleration cohort characteristics
From: Association of cardiovascular health and epigenetic age acceleration
Overall | EEAA T1 (< − 2.24 years.)Ref | EEAA T2 (− 2.24–2.33 years.) | EEAA T3 (> 2.33 years.) | |
|---|---|---|---|---|
N | 2170 | 724 | 727 | 719 |
Race/ethnicity (%) | ||||
Non-Hispanic Black or African-American | 554 (25.53) | 252 (34.81) | 178 (24.48)*** | 124 (17.25)*** |
Hispanic/Latino | 315 (14.52) | 62 (8.56) | 117 (16.09)*** | 136 (18.92)*** |
Non-hispanic white | 1083 (49.91) | 356 (49.17) | 352 (48.42) | 375 (52.16) |
Other | 218 (10.05) | 54 (7.46) | 80 (11)* | 84 (11.68)** |
Chronological age years (sd.) | 64.19 (7.06) | 64.35 (7.11) | 64.05 (7.09) | 64.19 (7) |
Education (%) | ||||
Less than high school | 198 (9.2) | 55 (7.66) | 61 (8.46) | 82 (11.5) |
High school diploma or GED | 395 (18.36) | 108 (15.04) | 141 (19.56)* | 146 (20.48)** |
Vocational, some college, associates | 848 (39.41) | 283 (39.42) | 295 (40.92) | 270 (37.87) |
College degree or greater | 711 (33.04) | 272 (37.88) | 224 (31.07)** | 215 (30.15)** |
Components of CVH score (%) | ||||
Non-smoking | 1,880 (87.81) | 634 (88.55) | 626 (87.31) | 620 (87.57) |
Ideal BMI | 521 (24.13) | 180 (25.07) | 188 (25.9) | 153 (21.4) |
Ideal physical activity | 428 (21.59) | 150 (22.9) | 153 (22.9) | 125 (18.97) |
Ideal cholesterol levels | 1,536 (79.22) | 505 (79.03) | 514 (78.47) | 517 (80.16) |
Ideal glucose levels | 1,928 (88.85) | 657 (90.75) | 640 (88.03) | 631 (87.76) |
Ideal blood pressure | 414 (19.08) | 147 (20.3) | 133 (18.29) | 134 (18.64) |
Ideal diet | 606 (27.93) | 205 (28.31) | 201 (27.65) | 200 (27.82) |
CVH score (%) | ||||
0–1 | 41 (2.16) | 13 (2.07) | 16 (2.48) | 12 (1.91) |
2 | 213 (11.2) | 59 (9.39) | 89 (13.82)** | 65 (10.33) |
3 | 636 (33.46) | 213 (33.92) | 188 (29.19) | 235 (37.36) |
4 | 574 (30.19) | 186 (29.62) | 207 (32.14) | 181 (28.78) |
5 | 294 (15.47) | 104 (16.56) | 94 (14.6) | 96 (15.26) |
6–7 | 143 (7.52) | 53 (8.44) | 50 (7.76) | 40 (6.26) |