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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines

Fig. 4

Graphical overview of the highest numbers of strong trans-correlations between GMD expression and methylation levels of target individual probes and gene regions in pancancer analysis. Shown are the counts of trans-correlations for GMDs presented in Table 2. Positive correlations are shown as red bars directed upward, whereas negative correlations are shown as blue bars directed downward. A. GMDs with trans-correlations with ≥ 5 probes which satisfied p < 1.389 × 10–8 and Spearman |ρ| > 0.5. B. GMDs with trans-correlations with ≥ 4 gene regions which satisfied pFDR < 0.05 and Spearman |ρ| > 0.5

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