Fig. 5
From: FK228 sensitizes radioresistant small cell lung cancer cells to radiation
Effects of FK228 and radiation on the DNA double-strand break formation and repair. a, b Representative images of immunofluorescent staining for γH2AX [31] and Rad51 (30) in SCLC cells upon treatment with FK228 (1 nM) or radiation (4 Gy) alone and in combination. Scale bar, 10 μm. Quantification of γH2AX (a) and Rad51 (b) fluorescence intensities from three independent experiments was shown in right panels. *p < 0.05, ***p < 0.001, ****p<0.0001; ns, no significance