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Fig. 2 | Clinical Epigenetics

Fig. 2

From: MicroRNAs overexpressed in Crohn’s disease and their interactions with mechanisms of epigenetic regulation explain novel aspects of Crohn’s disease pathogenesis

Fig. 2

Functional interaction network of enzymes associated with epigenetic and post-translational modifications, whose expression is regulated by miRNAs involved in Crohn's disease. Proteins were classified by String v11 software according to “(GO) Biological Process” distribution option. Each node represents all the proteins produced by a single protein-coding gene locus. Red nodes correspond to proteins involved in methylation (GO:0032259), blue nodes to histone modification (GO:0016570), dark green nodes to protein metabolic process (GO:0019538), light green nodes to nucleic acid metabolic process (GO:0090304), aquamarine nodes to protein ubiquitination (GO:0016567), yellow nodes to regulation of cell cycle process (GO:0010564) and pink nodes to regulation of immune system process (GO:0002682), respectively. Edges represent protein–protein action type associations

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