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Table 3 Logistic regression analyses of variables for complete remission in non-M3 AML patients

From: Identification and validation of obesity-related gene LEP methylation as a prognostic indicator in patients with acute myeloid leukemia

Variables Univariate analysis Multivariate analysis
Odds ratio (95% CI) P value Odds ratio (95% CI) P value
LEP methylation 0.452 (0.208–0.982) 0.045 0.330 (0.135–0.806) 0.015
Age 0.215 (0.091–0.509) 0.000 0.191 (0.076–0.479) 0.000
WBC 0.349 (0.157–0.778) 0.010 0.522 (0.215–1.266) 0.151
Cytogenetic risks 0.463 (0.239–0.899) 0.023 0.398 (0.189–0.838) 0.015
NPM1 mutations 2.005 (0.620–6.488) 0.246   
FLT3-ITD mutations 0.764 (0.180–3.251) 0.715   
C-KIT mutations 2.458 (0.392–15.426) 0.337   
N/K-RAS mutations 0.481 (0.122–1.902) 0.297   
DNMT3A mutations 0.605 (0.112–3.286) 0.561   
U2AF1 mutations Undermined 0.999   
IDH1/2 mutations 1.045 (0.167–6.555) 0.962   
SRSF2 mutations Undermined 0.999   
SETBP1 mutations 1.579 (0.096–26.002) 0.749   
  1. Variables including LEP methylation (hypermethylation vs. non-hypermethylation), age (≤ 60 vs. > 60 years), WBC (≥ 30 × 109 vs. < 30 × 109 /L), and gene mutations (mutant vs. wild-type). Multivariate analysis includes variables with P < 0.100 in univariate analysis
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