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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Genome-wide DNA methylation dynamics during epigenetic reprogramming in the porcine germline

Fig. 4

Methylome dynamics of functional genomic elements at the different time points for each sex. Number of replicates: D28M (n = 1), D32M (n = 2), D36M (n = 2), D39M (n = 2), D42M (n = 1), D28F (n = 1), D32F (n = 2), D36F (n = 2), D39F (n = 2), D42F (n = 1). a Clustered heatmap of imprinted genes in male and female germ cells on D28, D32, D36, D39, and D42. High methylation levels are represented in red, and low methylation levels are shown in blue. To the left, methylation levels in oocyte and sperm, data from [27]. b Heatmap showing the levels of methylation of the transposable elements analysed. Each line corresponds to a single probe. High methylation levels are represented in red, and low methylation levels are shown in blue. c Line graph representing the mean level of methylation for the same genomic features represented in b on each day. d Mean methylation levels of different subtypes of transposable elements: LINEs (left), SINEs (centre), and LTRs (right). The darker colour represents the evolutionary older element in each case

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