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Fig. 7 | Clinical Epigenetics

Fig. 7

From: H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade

Fig. 7

H3K27me3 expression in human melanoma cell lines after 72 h stimulation with TNFα or IFNy. Representative pictures of IHC of human melanoma cell line MaMel102 and human melanoma cell line MaMel15 in 40-fold magnification. MaMel15: a: untreated (Ctrl), displaying 3% H3K27me3 positive melanoma cells. b After stimulation with TNFα, displaying 3% H3K27me3 positive melanoma cells. c After stimulation with IFNy, displaying 3% H3K27me3 positive melanoma cells. MaMel 102: a untreated (Ctrl), displaying 10% H3K27me3 positive melanoma cells. b After stimulation with TNFα, displaying 10% H3K27me3 positive melanoma cells. c After stimulation with IFNy, displaying 10% H3K27me3 positive melanoma cells

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