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Fig. 5 | Clinical Epigenetics

Fig. 5

From: H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade

Fig. 5

H3K27me3 expression compared between primary melanomas and cutaneous melanoma metastases. a H3K23me3 expressing tumors (in %) comparing primary melanomas (n = 136) and cutaneous melanoma metastases (n = 84). Significance was determined by Χ2 test for categorical data. b H3K27me3 IHC staining of primary melanomas and cutaneous melanoma metastases in 5-fold and 40-fold magnification (from left to right). Cutaneous melanoma metastases show a more frequent expression of H3K27me3 in comparison to primary melanomas.

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Clinical Epigenetics

ISSN: 1868-7083

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