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Table 1 PM20D1 mQTL region genes and SNPs and their DNA methylation correlation obtained from the Hannon database

From: Comprehensive analysis of PM20D1 QTL in Alzheimer’s disease

 

CpG

rs1172198

rs708727

rs823082

rs823088

rs1361754

rs960603

Min

Max

Delta

NUCKS1

-

-

-

-

-

-

-

-

-

-

RAB7L1

-

-

-

-

-

-

-

-

-

-

SLC41A1

cg23034840

-

7.60E−08

-

2.90E−05

-

-

7

9

2

PM20D1

cg07157834

-

3.60E−22

-

-

-

-

83

90

7

PM20D1

cg24503407

4.60E−08

1.90E−25

7.20E−16

-

7.20E−16

1.80E−12

60

87

27

PM20D1

cg07167872

2.80E−07

5.00E−26

7.00E−16

4.10E−10

6.90E−16

1.90E−13

41

79

38

PM20D1

cg11965913

2.30E−11

2.30E−37

2.50E−19

1.50E−10

2.50E−19

1.30E−14

15

75

60

PM20D1

cg14893161

1.30E−12

4.30E−34

7.00E−19

1.30E−09

7.00E−19

1.40E−13

17

70

53

PM20D1

cg14159672

1.30E−08

3.00E−30

3.20E−18

1.20E−10

3.20E−18

3.10E−13

22

87

65

PM20D1

cg26354017

1.40E−09

5.60E−33

2.10E−18

4.50E−10

2.10E−18

1.10E−14

12

83

71

PM20D1

cg17178900

7.00E−08

1.20E−19

1.20E−13

-

1.20E−13

4.10E−09

40

87

47

  1. Values represent CpG DNA methylation and SNP correlation Bonferroni-corrected p values from Hannon et al. [14], n = 166 prefrontal cortex samples (https://epigenetics.essex.ac.uk/mQTL/). Min lowest value, Max highest value, Delta highest − lowest values. Significantly differentially probes for each gene are represented. “-,” not significant