Table 1 TOP10 downregulated miRs in CMML-MPDs of Kras^G12D mice. miRs were ranked according to their x-fold expression change in Kras^G12D mice as compared to the wildtype controls. Only statistically significant miRs with a mean signal intensity of > 4 on all arrays were selected

mmu-miR-99b-5p

MIMAT0000132

-4.13

 < 0.001

mmu-miR-125a-5p

MIMAT0000135

-3.89

 < 0.001

mmu-miR-130a-3p

MIMAT0000141

-3.59

0.001

mmu-miR-146a-5p

MIMAT0000158

-3.49

 < 0.001

mmu-miR-99a-5p

MIMAT0000131

-3.06

0.001

mmu-miR-676-3p

MIMAT0003782

-2.55

 < 0.001

mmu-miR-150-5p

MIMAT0000160

-2.44

 < 0.001

mmu-let-7e-5p

MIMAT0000524

-2.32

0.001

mmu-miR-26a-5p

MIMAT0000082

-1.71

0.001

mmu-miR-3535

MIMAT0031410

-1.63

 < 0.001