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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Association of variably methylated tumour DNA regions with overall survival for invasive lobular breast cancer

Fig. 1

Methylation pattern of invasive lobular breast cancer (ILBC) samples. Heatmaps show the methylation patterns of invasive lobular breast cancer (ILBC) samples in the Melbourne Collaborative Cohort Study (MCCS) across the ten most significant variably methylated regions (VMRs): a ISM1, b APC, c TMEM101, d ASCL2, e NKX6, f HIST3H2A, g HCG4P3, h HES5, i CELF2 j EFCAB4B. Annotation of CpGs by genomic position and location in the context of gene are marked on the maps. Annotation of samples by age at diagnosis and tumour characteristics are shown in the colour bars as indicated in the legend on the top-right. The methylation beta-value of the CpG positions shown in the heatmap is indicated in the colour key on the top-right corner

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