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Fig. 2 | Clinical Epigenetics

Fig. 2

From: DNA methylation signatures to predict the cervicovaginal microbiome status

Fig. 2

WID-LO-index performance in cervical samples. a Receiver operating characteristic curves for the linear classifier in the validation set. b, c WID-LO-index in the validation set, trend with IC (b) and with age (c). d Adjusted odds ratios for the association of WID-LO-index with community-type determined from sample microbiota proportions, Age < 50 years subgroup. See also Additional file 1: Fig. S7. (*) corresponds to adjustment for Age. (**) corresponds to adjustment for IC. (***) corresponds to adjustment for age and IC. Odds ratios, 95% confidence intervals and p values were calculated under a logistic regression model with a bias reduction method. IC = immune cell proportion. The WID-LO-index was generated with 819 selected CpGs. See “Methods” section for details

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