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Table 1 Detection rates of both assays according to histological/cytological and hrHPV findings (n = 195)

From: Triage of hrHPV-positive women: comparison of two commercial methylation-specific PCR assays

  GynTect® QIAsure Methylation Test P value for comparison of detection rate
Test positive Detection rate [%]
(95% CI)
Test positive Detection rate [%]
(95% CI)
hrHPV + 
 CxCa
(n = 2)
2 2/2* 2 2/2*
 CIS
(n = 5)
5 5/5* 5 5/5*
 CIN3
(n = 35)
21 60.0
(42.1–76.1)
26 74.3
(56.7–87.5)
0.125
 CIN2
(n = 18)
6 33.3
(13.3–59.0)
5 27.8
(9.7–53.5)
1.000
 CIN1
(n = 15)
2 13.3
(1.7–40.5)
4 26.7
(7.8–55.1)
0.500
 no CIN
(n = 21)
6 28.6
(11.3–52.2)
11 52.4
(29.8–74.3)
0.125
 NILM
(n = 53)
3 5.7
(1.2–15.7)
14 26.4
(15.3–40.3)
0.003
hrHPV − 
 NILM
(n = 46)
1 2.2
(0.1–11.5)
11 23.9
(12.6–38.8)
0.006
  1. *Due to the low number of cases we present absolute frequencies for description and omit percentages and statistical comparisons