Table 1 Demographic and clinical characteristics of the samples used in the EPIC array assay

Age at death (year), mean (SD)

80.65 (6.94)

81.00 (7.09)

0.717

81.00 (6.63)

81.13 (6.40)

0.967

Sex, male n (%)

37 (61.7)

39 (58.2)

0.692

36 (63.2)

35 (58.3)

0.593

PMI (hour), Mean (SD)

3.24 (2.02)

3.06 (1.60)

0.837

3.25 (2.05)

3.15 (1.69)

0.846

Estimated NeuN⁺ (%) Mean (SD)

30.3 (13.1)

29.6 (11.3)

0.504

24.5 (12.3)

28.1 (9.9)

0.159

Estimated NeuN⁻ (%), Mean (SD)

68.6 (14.1)

69.3 (12.7)

0.570

69.0 (15.4)

64.1 (12.0)

0.095

NIA-Reagan criteria [72], n

 Criteria not met

59

56

 Not AD

1

1

 Low

2

2

 Intermediate

16

17

 High

49

41

Semiquantitative measure of neuritic plaques CERAD score [73], n

 Criteria not met

6

6

 Not AD

33

31

 Possible AD

21

20

 Probable AD

8

8

 Definite AD

59

52

Braak stage, n

 I

15

12

 II

14

2

14

2

 III

20

4

21

4

 IV

11

12

10

13

 V

28

21

 VI

21

20

APOE genotype, n*

 ε2/ε2

1

0

2

0

 ε2/ε3

10

3

10

1

 ε3/ε3

32

26

30

26

 ε3/ε4

16

33

15

27

 ε2/ε4

0

1

0

1

 ε4/ε4

1

3

0

4