Table 1 Baseline clinical characteristics of enrolled subjects

Age

68.39 (5.08)

68.09 (5.16)

0.9

Gender (male %)

7 (50)

8 (66.7)

0.7

BMI (mean (SD))

31.06 (6.85)

26.71 (5.66)

0.09

Lifestyle

 Current smoker

0 (0)

0 (0)

1

 Former smoker

7 (50)

6 (50.0)

1

 Past smoker

7 (50)

6 (50.0)

1

 Pack-years (mean (SD))

9.50 [0–45]

4.00 [0–10.5]

0.06

Systolic BP (mean (SD))

142.93 (13.38)

127.5 (15.21)

0.01

Medical history

 AP (%)

7 (50)

0 (0)

0.02

 MI (%)

4 (28.6)

0 (0)

0.1

 CVA (%)

2 (14.3)

0 (0)

0.5

 PAD (%)

6 (42.9)

0 (0)

0.03

CRP (median [IQR])

1.50 [1.30–3.15]

1.35 [0.85–2.02]

0.3

Leukocytes (mean (SD))

6.59 (1.35)

5.57 (1.65)

0.1

Monocytes (mean (SD))

0.56 (0.17)

0.50 (0.13)

0.4

Glucose (median [IQR])

8,05 [7.30–10.15]

5.35 [5.20–5.60]

 < 0.001

Creatinine (median [IQR])

89.5 [84–113.75]

84.5 [66.5–92]

0.08

Total cholesterol (mean (SD))

3.97 (0.77)

5.48 (1.21)

0.001

HDL cholesterol (mean (SD))

1.31 (0.22)

1.73 (0.69)

0.04

LDL cholesterol (mean (SD))

1.93 (0.47)

3.23 (0.79)

< 0.001

Triglycerides (median [IQR])

1.39 [1.13–1.70]

0.85 [0.71–1.29]

0.02

Lp(a) (median [IQR])

103 [90–120.5]

87.5 [45.25–148.75]

0.9

Hba1c (median [IQR])

63 [54.5–66.75]

38.5 [38–39.25]

< 0.001

Statin use (%)

12 (85.7)

0

< 0.001

Insulin use (%)

10 (71.4)

0

0.001