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Table 1 Annotation of differentially methylated probes in the blue group

From: Epigenetic stratification of head and neck cancer survivors reveals differences in lycopene levels, alcohol consumption, and methylation of immune regulatory genes

Probe ID Gene Name Primary function Relation to island CpG location Regulatory feature Methylation
cg02010442a ATG4A Autophagy related 4A cysteine peptidase Autophagy Island 1st Exon, 5’UTR Promoter Hypomethylated
cg02010442a PSMD10 Proteasome 26S Subunit, Non-ATPase 10 Protein degradation Island TSS200 Promoter Hypomethylated
cg03219922 N/A N/A N/A Shore N/A N/A Hypermethylated
cg04621904 FAM47C Family with sequence similarity 47 member C Unknown Shore 1st Exon None Hypermethylated
cg06081716 SENP7 SUMO/Sentrin specific peptidase 7 SUMOylation Shore TSS1500 Promoter Hypermethylated
cg07917502b PREPL Prolyl endopeptidase like Proteolysis Island TSS200 Promoter Hypermethylated
cg07917502b CAMKMT Calmodulin-lysine N-methyltransferase Calcium signaling Island TSS200 Promoter Hypermethylated
cg09130556 CYP1B1 Cytochrome P450 family 1 subfamily B member 1 Cytochrome p450 Island TSS1500 Enhancer Hypermethylated
cg11585357 N/A N/A N/A Sea N/A Enhancer Hypomethylated
cg11754259 ZBTB44 Zinc finger and BTB domain containing 44 Transcription Island 1st Exon, 5’UTR None Hypermethylated
cg11873147 C1QL2 Complement C1q like 2 Complement protein Island Gene Body None Hypermethylated
cg14137558 UTP14A UTP14A, small subunit processome component Ribosomal protein Island TSS200 Promoter Hypomethylated
cg15682807 ITM2A Integral membrane protein 2A Membrane Protein Sea 1st Exon None Hypomethylated
cg15842967 KDM2A Lysine demethylase 2A Transcription, histone modification Sea Gene Body Promoter Hypermethylated
cg17145281 INTS5 Integrator Complex Subunit 5 Integrator complex with RNA Pol II Shore Gene Body Promoter Hypermethylated
cg17716100 FOXO4 Forkhead box O4 Transcription factor, lipid metabolism Island TSS1500 Promoter Hypomethylated
cg21888438 MID1IP1 MID1 interacting protein 1 Lipid metabolism Island Gene Body None Hypomethylated
cg24890023 XPO1 Exportin 1 Nuclear export Shore 5’UTR None Hypermethylated
cg26708638 ZNF444 Zinc finger protein 444 Transcription Island TSS200 Promoter Hypomethylated
cg27360006 ZNF41 Zinc finger protein 41 Transcription Sea Gene Body None Hypermethylated
cg27609596 PTCHD1 Patched domain containing 1 Membrane protein, autism Island TSS1500 None Hypomethylated
  1. 5’UTR: 5’ untranslated region, TSS200: within 200 bp of the transcription start site, TSS1500: within 1500 bp of the transcription start site. acg02010442 and bcg07917502 were each associated with two different genes.