Table 1 Annotation of differentially methylated probes in the blue group
Probe ID | Gene | Name | Primary function | Relation to island | CpG location | Regulatory feature | Methylation |
|---|---|---|---|---|---|---|---|
cg02010442a | ATG4A | Autophagy related 4A cysteine peptidase | Autophagy | Island | 1st Exon, 5’UTR | Promoter | Hypomethylated |
cg02010442a | PSMD10 | Proteasome 26S Subunit, Non-ATPase 10 | Protein degradation | Island | TSS200 | Promoter | Hypomethylated |
cg03219922 | N/A | N/A | N/A | Shore | N/A | N/A | Hypermethylated |
cg04621904 | FAM47C | Family with sequence similarity 47 member C | Unknown | Shore | 1st Exon | None | Hypermethylated |
cg06081716 | SENP7 | SUMO/Sentrin specific peptidase 7 | SUMOylation | Shore | TSS1500 | Promoter | Hypermethylated |
cg07917502b | PREPL | Prolyl endopeptidase like | Proteolysis | Island | TSS200 | Promoter | Hypermethylated |
cg07917502b | CAMKMT | Calmodulin-lysine N-methyltransferase | Calcium signaling | Island | TSS200 | Promoter | Hypermethylated |
cg09130556 | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1 | Cytochrome p450 | Island | TSS1500 | Enhancer | Hypermethylated |
cg11585357 | N/A | N/A | N/A | Sea | N/A | Enhancer | Hypomethylated |
cg11754259 | ZBTB44 | Zinc finger and BTB domain containing 44 | Transcription | Island | 1st Exon, 5’UTR | None | Hypermethylated |
cg11873147 | C1QL2 | Complement C1q like 2 | Complement protein | Island | Gene Body | None | Hypermethylated |
cg14137558 | UTP14A | UTP14A, small subunit processome component | Ribosomal protein | Island | TSS200 | Promoter | Hypomethylated |
cg15682807 | ITM2A | Integral membrane protein 2A | Membrane Protein | Sea | 1st Exon | None | Hypomethylated |
cg15842967 | KDM2A | Lysine demethylase 2A | Transcription, histone modification | Sea | Gene Body | Promoter | Hypermethylated |
cg17145281 | INTS5 | Integrator Complex Subunit 5 | Integrator complex with RNA Pol II | Shore | Gene Body | Promoter | Hypermethylated |
cg17716100 | FOXO4 | Forkhead box O4 | Transcription factor, lipid metabolism | Island | TSS1500 | Promoter | Hypomethylated |
cg21888438 | MID1IP1 | MID1 interacting protein 1 | Lipid metabolism | Island | Gene Body | None | Hypomethylated |
cg24890023 | XPO1 | Exportin 1 | Nuclear export | Shore | 5’UTR | None | Hypermethylated |
cg26708638 | ZNF444 | Zinc finger protein 444 | Transcription | Island | TSS200 | Promoter | Hypomethylated |
cg27360006 | ZNF41 | Zinc finger protein 41 | Transcription | Sea | Gene Body | None | Hypermethylated |
cg27609596 | PTCHD1 | Patched domain containing 1 | Membrane protein, autism | Island | TSS1500 | None | Hypomethylated |